World Health Day 2025

 

Association between Vitamin D and Dengue Severity: A Systematic Review and Meta-Analysis Protocol

Abstract

Purpose: To understand how vitamin D influences the severity of dengue fever as per WHO 1997 and WHO 2009 classification, as many studies have shown ambiguity in this respect Method: The review has been registered in PROSPERO with registration number CRD420251003676 and will be carried out in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) 2020 standards. Peer-reviewed literature will be used to identify the studies. The literature search will be conducted using the following databases: Web of Science, PubMed, PubMed Central, and Scopus. Additionally, the academic search engine - Google Scholar will be searched; two reviewers will independently screen the titles and abstracts of studies based on predefined eligibility criteria. The other two reviewers will assess the quality based on the Joanna Briggs Institute quality parameters. Heterogeneity among the included studies will be examined using statistical measures such as I2 and Cochrane Q statistics. Sensitivity and subgroup analysis will be used to assess the findings’ reliability. If there are more than ten articles, a funnel plot test will be employed to assess publication bias. Conclusion: This systematic review and meta-analysis, in the absence of multi-centric studies, will explore whether Vitamin D deficiency worsens dengue outcomes and if supplementation could help. The findings from this study could help shape future treatments and improve patient care. In areas where dengue is endemic, our systematic review and meta-analysis will assist in pinpointing research gaps and direct future studies and public health initiatives. 

 Keywords: Dengue Fever, Dengue Haemorrhagic Fever, Vitamin D

 Agarwal S J, Jena P K, Kishore J, Sahu L S, Behera C K, Panda S K, Agarwal V. Association between Vitamin D and Dengue Severity: A Systematic Review and Meta-Analysis Protocol. J Commun Dis. 2025;57(1):151-156.

DOI: https://doi.org/10.24321/0019.5138.202520

Nationwide insights into frailty: Systematic review and meta-analysis of community-based prevalence studies from India

 

Sunanda Gupta, Aninda Debnath, Ankit Yadav, Anubhav Mondal, Shweta Charag, Jugal Kishore. Nationwide insights into frailty: Systematic review and meta-analysis of community-based prevalence studies from India. The Journal of Frailty & Aging. 2025; 14 (2) 100032; https://doi.org/10.1016/j.tjfa.2025.100032

Frailty, a biologic syndrome of decreased reserve and resistance to stressors, affects 5 % to 17 % of older adults and is linked to factors like low BMI, female sex, and low exercise levels. With India's older population expected to double by 2050, frailty presents major public health and economic challenges. This study summarizes the prevalence of frailty among community-dwelling Indians. This systematic review and meta-analysis followed PRISMA guidelines to determine the prevalence of frailty among adults in India. We conducted a comprehensive search across multiple databases, including PubMed, Scopus, EMBASE, and Web of Science, up to January 16, 2024, excluding hospital-based studies and reviews. Data were analyzed using STATA software with a random-effects model, and quality was assessed using the JBI Critical Appraisal Checklist. The meta-analysis revealed a pooled frailty prevalence of 36 % (95 % CI: 29 % to 44 %) among 330,007 community-dwelling adults in India, with significant heterogeneity across studies (I² = 99.95 %). Frailty prevalence varied by assessment method, with 48 % using the frailty index and 31 % using the Fried phenotype. Subgroup analyses indicated significant variability in frailty prevalence by gender, data source, and assessment tool, with no significant publication bias detected. This meta-analysis found a pooled frailty prevalence of 36 % and pre-frailty prevalence of 48 % among adults in India, with higher frailty in women (45 %) than men (35 %) and variation across assessment tools. Future research should focus on longitudinal studies and developing tailored frailty assessment tools.

"Social Media and Adolescent Psyche"

Social media has become a very influential medium for information and marketing activities. It transcended the spatial boundaries, throwing the limits and constraints into bits and has trapped the whole world into its web through the lucrative and prolific functions it offers to its users. Interacting with people and posting limitless new ideas and opinions on social media has increased creativity and social responsibility, but has also hurled users into a life of mental fury, restlessness, and social isolation. The speed of providing information at the earliest and providing a bunch of entertainment through various platforms has affected the mental health of teenagers badly. 

Dissemination of knowledge, information, and entertainment, in the blink of time, has posed a big threat to adolescent psychology. This approach of intercultural adaptation, not as per the level of citizens, but its easy access has speeded up the process of isolation and has increased various health issues in our present Generation Z who are easy prey to this technological growth. Kids tend to think that it’s their way of living. Mixing reels with real, cyberbullying, MMS, online abuse, nudity, adult content, crime, and drugs, are now very easily accessible to children, and the increasing data confirms it as the outcome of internet culture hurling them in deteriorated mental health, making teenagers suffer from school anxiety, depression, panic attack sleeplessness, childhood fears, persistent sadness and above all the overpowering feeling of loneliness. This paper states how the excessive use of the internet and social media badly damages the mental health of a teenager whose brain is passing through a highly sensitive period between the ages of 10 to 19, a perfect time when identities and feelings of self-worth are forming.

Keywords: Bedroom Culture, Adolescent Psychiatry, Cyberbullying, Isolation, Technological Growth, Panic Attacks 

Fatma I, Kishore J. Social Media and Adolescent Psyche. Ind J Youth Adol Health. 2024;11(3):1-5.

https://medical.advancedresearchpublications.com/index.php/IndianJ-YouthandAdolescentHeatlh/article/view/4324